DENVER, CO, March 20, 2026 (GLOBE NEWSWIRE) — The International Down Syndrome Basis (GLOBAL) is proud to announce that the Company for Healthcare Analysis and High quality (AHRQ) systemic assessment of the brand new version of the GLOBAL Scientific Care Tips for Adults with Down Syndrome (GLOBAL Grownup Tenet) has been printed nowadays within the prestigious Efficient Well being Care (EHC) Database.
That is the most important milestone within the 5-to-7-year rigorous construction procedure required to post skilled, evidence-based clinical checklist. The ECH newsletter contains up to date findings on occurrence and remedy for commonplace co-occurring stipulations and paves the best way for the 2nd Version of the GLOBAL Grownup Tenet, which will have to be finalized by means of the top of 2026 or early 2027. The brand new version updates and expands the primary version, which was once printed in JAMA in 2020 and established the primary evidence-based requirements for the grownup Down syndrome neighborhood. The JAMA newsletter was once probably the most visited clinical advice pages at the JAMA web site and so far has been professionally referenced over 200 occasions.
“So to announce this in time for International Down Syndrome Day is especially significant, stated GLOBAL Vice President of Analysis and Scientific Care Bryn Gelaro. “This publication, led by PICORI and AHRQ, is a powerful validation of the rigor we bring to Down syndrome research and medical care. By vetting clinical expertise against hard evidence, we are finally providing a reliable resource for medical professionals to ensure adults with Down syndrome receive the specialized, high-quality care they deserve.”
In 2023, GLOBAL was awarded a competitive grant from the Patient-Centered Outcomes Research Institute (PCORI). This grant funded a milestone systematic review designed to answer the GLOBAL Adult Guideline authors’ critical health questions and synthesize clinical expertise and research evidence. To ensure the highest level of objectivity, the AHRQ—the federal agency tasked with improving the safety and quality of America’s healthcare system—was commissioned to lead the comprehensive review of the literature.
The quality of the AHRQ review manuscript earned immediate publication in the EHC Database. In addition, the publication was acknowledged as a vital contribution to national health standards by the Director of AHRQ at the U.S. Department of Health and Human Services (HHS), Roger D. Klein, MD, JD.
“The GLOBAL Adult Guideline is important to my life,” says 2026 GLOBAL Ambassador Letizia Napoleone. “When I go to the doctor, I want to get better! They need to know about Down syndrome. I am proud to be part of GLOBAL who is helping doctors understand how to support people with Down syndrome to have healthy long lives.”
“We are deeply grateful to donors – including Key Collaborators and GLOBAL Member Organizations who understand the importance of this resource and have committed funds in support updates and the addition of important new medical cares,” says GLOBAL President & CEO Michelle Sie Whitten. It is usually a testomony to Bryn Gelaro and David Tolleson who’ve labored so diligently to make sure that the Tenet Workgroup can proceed the complicated job of rigorous assessment, superb writing, and newsletter. As a mother to Sophia, it’s glorious to understand that she’s going to get infinitely higher care in her outdated age on account of this useful resource.”
The AHRQ systematic assessment will at once tell the 2d Version GLOBAL Grownup Tips. Whilst the primary version addressed 9 essential spaces— Conduct, Alzheimer’s/Dementia, Diabetes, Heart problems, Weight problems, Osteoporosis, Atlantoaxial Instability, Thyroid Illness, and Celiac Illness, and Thyroid Problems—the brand new version will construct on that basis to incorporate 5 further subjects:
Blood CancersSolid Tumor (Cancers)Sleep Apnea Eye and VisionMusculoskeletal
“Our circle of relatives is venerated to fortify the GLOBAL Scientific Care Tips for Adults with Down Syndrome,” says Michele Ritter, a long-time GLOBAL supporter. “Having lost my beautiful sister Lorraine to Alzheimer’s, we know firsthand the gaps in medical care for adults with Down syndrome. We are proud and excited to support the 2nd edition and to see the impact these guidelines will have on the health and longevity of our loved ones around the world.”
Fifty-four GLOBAL Member Organizations have supported the 2nd Edition GLOBAL Adult Guideline. One of the largest multi-year donors, the Down Syndrome Alliance of the Midlands (DSA), based in Omaha, Nebraska, is grateful for GLOBAL’s efforts to establish this first-in-kind resource.
“For our families in the Midlands, these guidelines are more than just research—they are a lifeline,” said DSA Executive Director Elizabeth Draney. “It is great to have federal support but equally important, the GLOBAL Adult Guideline is something that doctors in our community trust and can help ensure our adult with Down syndrome receive the best care possible. We pledged our support for the second edition because investing in the guideline is an investment in the health of every person with Down syndrome.”
In 2018 GLOBAL effectively lobbied and advocated for the primary trans-Nationwide Institutes of Well being Down syndrome investment program referred to as the INCLUDE Mission. Within the time because the first version of the GLOBAL Grownup Tenet was once printed, the NIH INCLUDE Mission has equipped over $440M of investment to Down syndrome analysis this is contributing to the proof that’s the very basis of the ideas. As well as, the INCLUDE Mission analysis is bolstering the proof that contributes to the GLOBAL Grownup Tenet evidenced by means of the 2d Version having 300% extra high quality publications to attract from.
Checklist of GLOBAL Grownup Tenet Authors: Scientific Director at College of Pittsburgh Grownup Down Syndrome Middle, Peter Bulova (MD), Scientific Director of the Down Syndrome Hospital and Analysis Middle at Kennedy Kreiger, George Capone (MD), Scientific Director and Co-Founder, Recommend Scientific Crew Grownup Down Syndrome Middle in Chicago, Brian Chicoine (MD), Government Director of the Linda Crnic Institute for Down Syndrome at College of Colorado Anschutz Scientific Campus, Aurora, CO Joaquín Espinosa(PhD), Scientific Director of Immunogenetics and Transplantation Laboratory on the College of Arkansas for Scientific Sciences, Terry Harville (MD), Surgical Director of the Advanced Obstructive Sleep Apnea Middle on the College of Cincinnati, Christine Heubi (MD), Assistant Professor within the Division of Bodily Remedy on the College of Nevada, Thessa Hilgenkamp (PhD), Professor of Ophthalmology on the College of Pittsburgh College of Medication, Vishal Jhanji (MD), Scientific Director, Grownup Down Syndrome Hospital at Denver Well being, Barry Martin, MD, Leader of Pediatric Ophthalmology at Kids’s Health center Colorado, Emily McCourt (MD), Director of the Down Syndrome Behavioral Well being Collaborative, College of Colorado College of Medication Lina Patel (PsyD), Co-founder of the Adults with Down Syndrome Distinctiveness Hospital on the College of Kansas Scientific Middle, Moya Peterson (PhD, ARNP), Director of Scientific Scholar Training, College of Colorado Anschutz Scientific Campus, Michael Puente Jr (MD), Scientific Director of the Alzheimer’s Healing Analysis Institute and Alzheimer’s Medical Trials Consortium – Down Syndrome Foremost Investigator at Keck College of Medication of College of Southern California, Michael Rafii (MD, PhD), Professor of Circle of relatives and Group Medication at Cleveland Hospital Lerner School of Medication and Case Western Reserve College College of Medication Carl Tyler (MD), and Supplier on the Down Syndrome Middle of Western PA and Scientific Director of Boulevard Medication Pitt on the College of Pittsburgh Scientific Middle, Anna Marie White (MD).
To be told extra concerning the GLOBAL Scientific Care Tips for Adults with Down Syndrome talk over with https://www.globaldownsyndrome.org/medical-care-guidelines-for-adults/.
###
In regards to the International Down Syndrome FoundationThe International Down Syndrome Basis (GLOBAL) is the most important non-profit within the U.S. operating to avoid wasting lives and dramatically strengthen well being results for other people with Down syndrome. GLOBAL established the primary Down syndrome analysis institute and helps over 400 scientists and over 2,700 sufferers with Down syndrome from 40 states and 11 international locations. Running carefully with Congress and the Nationwide Institutes of Well being, GLOBAL is the lead advocacy group within the U.S. for Down syndrome analysis and care. GLOBAL has a club of over 130 Down syndrome organizations international, and is a part of a community of Associates – the Crnic Institute for Down Syndrome, the Sie Middle for Down Syndrome, the College of Colorado Alzheimer’s and Cognition Middle – all at the Anschutz Scientific Campus, and the GLOBAL Grownup Down Syndrome Hospital at Denver Well being.
GLOBAL’s extensively circulated clinical publications come with International Scientific Care Tips for Adults with Down Syndrome, Prenatal & New child Down Syndrome Data, and the award-winning mag Down Syndrome International TM. GLOBAL additionally organizes the yearly AcceptAbility Gala in Washington DC, andthe annual Be Gorgeous Be Your self Style Display, the most important Down syndrome fundraiser on the earth. Discuss with globaldownsyndrome.org and practice us on social media Fb, X, Instagram, LinkedIn, and YouTube.
GLOBAL Scientific Care Tips for Adults with Down Syndrome (GLOBAL Grownup Tenet)
GLOBAL Scientific Care Tips for Adults with Down Syndrome (GLOBAL Grownup Tenet)
